Molecular alchemy of the tumor suppresso
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Catherine MΓ©plan; Pierre Hainaut
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Article
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1999
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John Wiley and Sons
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English
β 769 KB
The p53 protein is an ubiquitous multifunction, zinc-binding transcription factor that is activated in response to multiple forms of stress and that controls proliferation, survival, DNA repair, and differentiation of cells exposed to potentially genotoxic DNA-damage. Loss of p53 function by mutatio