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Overexpression of p53 protein in human tumors

โœ Scribed by Inoue, Keiji; Kurabayashi, Atsushi; Shuin, Taro; Ohtsuki, Yuji; Furihata, Mutsuo


Book ID
118733606
Publisher
Springer
Year
2012
Tongue
English
Weight
732 KB
Volume
45
Category
Article
ISSN
0918-4287

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๐Ÿ“œ SIMILAR VOLUMES


Human breast cancer: frequent p53 allele
โœ S. Singh; M. Simon; I. Meybohm; I. Jantke; W. Jonat; H. Maass; H. W. Goedde ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Springer ๐ŸŒ English โš– 786 KB

A sample of 114 primary breast tumors and corresponding constitutional DNA were tested for loss of heterozygosity (LOH) of the YNZ22 and p53 genes, both located in the 17p13 region. Loss of the p53 allele was found in 28 of 44 primary breast carcinomas (64%). In contrast LOH in only 26 of 61 tumors