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Tumor-targeting properties of 90Y- and 177Lu-labeled α-melanocyte stimulating hormone peptide analogues in a murine melanoma model

✍ Scribed by Yubin Miao; Timothy J. Hoffman; Thomas P. Quinn


Book ID
116798868
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
236 KB
Volume
32
Category
Article
ISSN
0969-8051

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Six alpha-MSH(4-10) [Nle-Asp-His-D-Phe-Arg-Trp-Lys-amide] derivatives carrying 2 or 1 or no 2,3-dihydroxy-(2S)-propyl (DHP) groups on the Lys10 amino side chain were coupled to diethylene-triaminopentaacetic acid (DTPA, a chelator for 111In) in monomeric and dimeric forms and tested for their bindin