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Reducing renal uptake of 90Y- and 177Lu-labeled alpha-melanocyte stimulating hormone peptide analogues

✍ Scribed by Yubin Miao; Darrell R. Fisher; Thomas P. Quinn


Book ID
116799018
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
299 KB
Volume
33
Category
Article
ISSN
0969-8051

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## Abstract The purpose of our study was to optimize melanoma tumor uptake of ^188^Re‐CCMSH and reduce its nonspecific kidney retention. Nephrotoxicity is often a serious problem associated with targeted radiotherapy, therefore, increasing the tumor/kidney uptake ratio of ^188^Re‐CCMSH is crucial f