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Tumor suppressor p53 and its mutants in cancer metabolism

✍ Scribed by Liu, Juan; Zhang, Cen; Hu, Wenwei; Feng, Zhaohui

Book ID
122431227
Publisher
Elsevier Science
Year
2015
Tongue
English
Weight
847 KB
Volume
356
Category
Article
ISSN
0304-3835

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## Abstract Drug resistance remains a key obstacle to successful cancer treatment. The implementation of pharmacogenomics is widely proclaimed as a route to revolutionize the face of cancer therapy. Here we discuss the pharmacogenomics of the p53 tumor suppressor and its role in cancer chemosensiti