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Tumor Suppressor Gene Smad4/DPC4, Its Downstream Target Genes, and Regulation of Cell Cyclea

✍ Scribed by PAUL J. CHIAO; KELLY K. HUNT; ANA M. GRAU; ARAM ABRAMIAN; JASON FLEMING; WEI ZHANG; TARA BRESLIN; JAMES L. ABBRUZZESE; DOUGLAS B. EVANS

Book ID: 111395775
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 193 KB
Volume: 880
Category: Article
ISSN: 0890-6564
DOI: 10.1111/j.1749-6632.1999.tb09507.x

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## Abstract The ECRG4 gene was initially identified and cloned in our laboratory from human normal esophageal epithelium (GenBank accession no. AF325503). We revealed the expression of ECRG4 protein was downregulated in 68.5% (89/130) ESCC samples using tissue microarray. The low ECRG4 protein expr