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Tumor suppressor functions of FBW7 in cancer development and progression

✍ Scribed by Zhiwei Wang; Hiroyuki Inuzuka; Jiateng Zhong; Lixin Wan; Hidefumi Fukushima; Fazlul H. Sarkar; Wenyi Wei

Book ID
113622961
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
723 KB
Volume
586
Category
Article
ISSN
0014-5793

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✍ Peggy Ozenne; Beatrice Eymin; Elisabeth Brambilla; Sylvie Gazzeri πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 French βš– 209 KB

## Abstract The INK4b‐ARF‐INK4a locus encodes two members of the INK4 family of cyclin‐dependent kinase inhibitors, p15^INK4b^ and p16^INK4a^, and a completely unrelated protein called ARF. ARF is a nucleolar protein with unusual structure that exhibits tumor suppressive functions. There is growing