Tumor suppressor function of RUNX3 in breast cancer
β Scribed by Lin-Feng Chen
- Book ID
- 112120134
- Publisher
- John Wiley and Sons
- Year
- 2012
- Tongue
- English
- Weight
- 250 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0730-2312
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Rab proteins are a group of ubiquitously expressed proteins that are responsible for intracellular transport of vesicles. Recent evidence has shown that certain Rab proteins are involved in the pathogenesis of cancer. We have recently shown that Rab25 is lost in a large fraction of brea
The genetic determinants for most breast cancer cases remain elusive. However, a mutation in a tumor suppressor gene, such as p53, BRCA1, BRCA2, or ATM, has been determined to be one mechanism of breast carcinogenesis. It has been established that inherited mutations in p53, BRCA1, and BRCA2 signifi
## Abstract Loss of heterozygosity on the long arm of chromosome 16 is one of the most frequent genetic events in breast cancer, suggesting the presence of one or more classic tumorβsuppressor genes (TSGs). It has been shown that Eβcadherin is the TSG on 16q in lobular tumors. In a search for the t