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Tumor necrosis factor-α pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury

✍ Scribed by Lynne J. Eddy; David V. Goeddel; Grace H.W. Wong

Book ID
115765055
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
505 KB
Volume
184
Category
Article
ISSN
0006-291X

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Although hepatic ischemia-reperfusion (IR) injury is partially mediated by tumor necrosis factor-alpha (TNF), we recently found that low-dose TNF before IR is hepatoprotective. We examined the seemingly conflicting roles of TNF in mediating liver injury in a partial hepatic IR model using TNF gene k