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Increased Myocardial Tumor Necrosis Factor-α in a Crystalloid-Perfused Model of Cardiac Ischemia-Reperfusion Injury

✍ Scribed by Daniel R. Meldrum MD; Joseph C. Cleveland Jr; MD; Brian S. Cain MD; Xianzhong Meng MD; PhD; Alden H. Harken MD

Book ID
117038349
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
316 KB
Volume
65
Category
Article
ISSN
0003-4975

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Although hepatic ischemia-reperfusion (IR) injury is partially mediated by tumor necrosis factor-alpha (TNF), we recently found that low-dose TNF before IR is hepatoprotective. We examined the seemingly conflicting roles of TNF in mediating liver injury in a partial hepatic IR model using TNF gene k