𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tumor necrosis factor-α inhibits chondrogenic differentiation of synovial fibroblasts through p38 mitogen activating protein kinase pathways

✍ Scribed by Chiaki Okuma-Yoshioka; Hiroaki Seto; Yuho Kadono; Atsuhiko Hikita; Yasushi Oshima; Hisashi Kurosawa; Kozo Nakamura; Sakae Tanaka

Publisher
Springer
Year
2008
Tongue
English
Weight
784 KB
Volume
18
Category
Article
ISSN
1439-7595

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Interleukin (IL)-17 enhances tumor necro
Interleukin (IL)-17 enhances tumor necrosis factor-α-stimulated IL-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts
✍ Haruhiko Tokuda; Yosuke Kanno; Akira Ishisaki; Motoki Takenaka; Atsushi Harada; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 184 KB

## Abstract Inflammatory cytokines are well known to play crucial roles in the pathogenesis of rheumatoid arthritis. Among them, interleukin (IL)‐17 is a cytokine that is mainly synthesized by activated T cells and its receptors are present in osteoblasts. The synthesis of IL‐6, known to stimulate

Differential induction of tumor necrosis
Differential induction of tumor necrosis factor α and manganese superoxide dismutase by endotoxin in human monocytes: Role of protein tyrosine kinase, mitogen-activated protein kinase, and nuclear factor κB
✍ Julie E. White; Hung-Yun Lin; Faith B. Davis; Paul J. Davis; Min-Fu TsanSup–Sup 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB 👁 1 views

A mutant Escherichia coli lipopolysaccharide (LPS) lacking myristoyl fatty acid markedly stimulates the activity of manganese superoxide dismutase (MnSOD) without inducing tumor necrosis factor ␣ (TNF␣) production by human monocytes (Tian et al., 1998, Am J Physiol 275:C740.), suggesting that induct

p38 Mitogen-activated protein kinase mod
p38 Mitogen-activated protein kinase modulates expression of tumor necrosis factor-related apoptosis-inducing ligand induced by interferon-γ in fetal brain astrocytes
✍ J. Lee; J.-S. Shin; J.Y. Park; D. Kwon; S.-J. Choi; S.-J. Kim; I.-H. Choi 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 239 KB

## Abstract This study describes the involvement of the p38 mitogen‐activated protein kinase (MAPK) during interferon‐γ (IFN‐γ) signaling in fetal brain astrocytes. In some pathological conditions of brain, p38 MAPK transduces stress‐related signals, increases expression of proinflammatory cytokine