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Tumor necrosis factor-α gene promoter polymorphism in coal worker' pneumoconiosis

✍ Scribed by Kyoung Ah Kim; Yong-Yeun Cho; Jung Sik Cho; Ki Hwa Yang; Woon Kyu Lee; Kweon-Haeng Lee; Yun Shin Kim; Young Lim


Book ID
110343497
Publisher
Springer
Year
2002
Tongue
English
Weight
65 KB
Volume
234/235
Category
Article
ISSN
0300-8177

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Tumor necrosis factor-␣ (TNF) is recognized as a central mediator of mineral dust-induced lung fibrosis, and genetic polymorphisms of the TNF promoter have been reported to influence levels of TNF production. To assess whether polymorphisms within the TNF promoter gene are associated with susceptibi