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Tumor necrosis factor modulates transcription of myelin basic protein gene through nuclear factor kappa B in a human oligodendroglioma cell line

✍ Scribed by Chang J Huang; Ramin Nazarian; Justin Lee; Paul M Zhao; Araceli Espinosa-Jeffrey; Jean de Vellis


Book ID
117563576
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
341 KB
Volume
20
Category
Article
ISSN
0736-5748

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✍ Pablo M. Paez; Corina I. GarcΓ­a; Juana M. Pasquini πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 622 KB

We have shown that apotransferrin (aTf) promotes the differentiation of two oligodendroglial cell (OLGc) lines, N19 and N20.1, representing different stages of OLGc maturation. Although in both cell lines aTf promoted myelin basic protein (MBP) expression, an increase in cAMP levels and CREB phospho