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A COMBINATION OF S-1 AND DOCETAXEL ACTS SYNERGISTICALLY BY MODULATING METABOLIC ENZYME AND NUCLEAR FACTOR-KAPPA B ACTIVITY IN A HUMAN PROSTATE CANCER CELL LINE

โœ Scribed by Hasegawa, Masanori; Miyajima, Akira; Yasumizu, Yota; Ide, Hiroki; Kosaka, Takeo; Kikuchi, Eiji; Oya, Mototsugu


Book ID
122532474
Publisher
Lippincott Williams and Wilkins
Year
2009
Tongue
English
Weight
71 KB
Volume
181
Category
Article
ISSN
0022-5347

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## Abstract We have recently demonstrated in a Phase I/II study that combination chemotherapy with docetaxel (TXT) and Sโ€1 is active against metastatic gastric carcinomas. To elucidate the mechanisms underlying the synergistic effects of these drugs, both the growth inhibitory effects and the expre