Tumor Necrosis Factor and Alcoholic Liver Disease
β Scribed by Craig J. McClain; Shirish Barve; Swati Barve; Ion Deaciuc; Daniell B. Hill
- Book ID
- 109120154
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 583 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0145-6008
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We investigated the potential of dietary saturated fatty acids to decrease endotoxemia and suppress expression of cyclooxygenase 2 (Cox-2) and tumor necrosis factor alpha (TNF-alpha) in established alcohol-induced liver injury. Six groups (five rats/group) of male Wistar rats were studied. Rats in g
The proinflammatory cytokines interleukin-1 and tumor necrosis factor-alpha are thought to play important roles in the pathophysiology of liver disease. Specific antagonists of these cytokines have been found in recent years. Interleukin-1 receptor antagonist is a specific interleukin-1 antagonist.