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Tumor necrosis factor-alpha gene promoter polymorphism in patients with familial Mediterranean fever

✍ Scribed by Arzu Celebi Kobak; Senol Kobak; Yasemin Kabasakal; Ulus Salih Akarca

Publisher
Springer
Year
2006
Tongue
English
Weight
81 KB
Volume
26
Category
Article
ISSN
0770-3198

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The striking evidence of almost 100% association of narcolepsy with human leukocyte antigens (HLA) DR2(DR15) antigen is an important clue to elucidate the molecular basis of this sleep disorder. The gene for tumor necrosis factor ␣ (TNF ␣) is located in the HLA class II gene cluster. Recent studies