𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Tumor Cells Transfected with B7-1 and Interleukin-12 cDNA Induce Protective Immunity

✍ Scribed by PETER W. CHEN; DAVID C. GEER; ECKHARD R. PODACK; BRUCE R. KSANDER

Book ID
119873634
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
146 KB
Volume
795
Category
Article
ISSN
0890-6564

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Vaccination of tumor cells transfected w
Vaccination of tumor cells transfected with the B7-1 (CD80) gene induces the anti-metastatic effect and tumor immunity in mice
✍ Hideki Fujii; Manabu Inobe; Fuminari Kimura; Jun Murata; Masaaki Murakami; Yasuh πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 French βš– 766 KB

The present study demonstrates that the transfection of B7-I or its variant MB7-2 genes into MHC class I+ tumor cells (B 16-BL6 or K I 735-M2 melanoma) resulted in the remarkable reduction of lung metastasis caused by i.v. injection into immunocompetent syngeneic mice. However, i.v. injection of the

B7-1 (CD80)-gene transfer combined with
B7-1 (CD80)-gene transfer combined with interleukin-12 administration elicits protective and therapeutic immunity against mouse hepatocellular carcinoma
✍ Tomohide Tatsumi; Tetsuo Takehara; Tatsuya Kanto; Noriyoshi Kuzushita; Akihiko I πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 113 KB

Human hepatocellular carcinoma (HCC) frequently recurs after primary therapy, resulting in poor prognosis. To try to find a way to prevent this, we examined the combined effectiveness of B7-1 (CD80)-gene transfer and interleukin-12 (IL-12) on the induction of protective antitumor immunity against po