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Tumor-cell killing by MAbs against fucosyl GM1, a ganglioside antigen associated with small-cell lung carcinoma


Book ID
123553008
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
160 KB
Volume
8
Category
Article
ISSN
0169-5002

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Tumor-cell killing by MAbs against fucos
✍ Fred-Thomas Brezicka; Jan Holmgren; Inge Kalies; Leif Lindholm πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 French βš– 1013 KB

Monoclonal antibodies (MAbs) reactive with the ganglioside fucosyl GM I (Fuc-GM I), an antigen associated with small-cell carcinoma of the lung (SCLC), were tested for their ability to mediate tumor-cell killing in vitro in conjunction with humoral and cellular effectors and to inhibit tumor engraft