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Fucosyl-GM1— A ganglioside associated with small cell lung carcinomas

✍ Scribed by Olle Nilsson; Jan-Erik MÅnsson; Tomas Brezicka; Jan Holmgren; Leif Lindholm; Sverre Sörenson; Fridrik Yngvason; Lars Svennerholm


Book ID
105333067
Publisher
Springer US
Year
1984
Tongue
English
Weight
590 KB
Volume
1
Category
Article
ISSN
1573-4986

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Tumor-cell killing by MAbs against fucos
✍ Fred-Thomas Brezicka; Jan Holmgren; Inge Kalies; Leif Lindholm 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 1013 KB

Monoclonal antibodies (MAbs) reactive with the ganglioside fucosyl GM I (Fuc-GM I), an antigen associated with small-cell carcinoma of the lung (SCLC), were tested for their ability to mediate tumor-cell killing in vitro in conjunction with humoral and cellular effectors and to inhibit tumor engraft