Tumor cell invasiveness correlates with changes in integrin expression and localization
β Scribed by Maschler, Sabine; Wirl, Gerhard; Spring, Herbert; Bredow, Dorothea v; Sordat, Isabelle; Beug, Hartmut; Reichmann, Ernst
- Book ID
- 110069481
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 459 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0950-9232
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
We have previously observed that acellular extracts from necrotic areas (NE) of the non-metastatic murine mammary adenocarcinoma M3, enhance in vitro cell detachment and spontaneous lung metastases. In the present study, using different proteinase inhibitors along with NE, only the calcium chelator
During the process of tumor cell invasion and metastasis, tumor cells are known to interact with extracellular matrix proteins, endothelial cells, platelets and other organ-specific structures. Integrins are cell surface molecules which mediate cell-matrix and cell-cell interactions and are likely t
## Abstract Understanding the molecular background of breast cancer biology is critical in developing new biomarkers for earlier diagnosis and more optimized treatment. We performed a proteomic analysis of human breast carcinoma tissues to investigate the tumorβspecific protein expression in breast