Tumor Angiogenesis Inhibitors
โ Scribed by S. M. Kiselev; S. V. Lutsenko; S. E. Severin; E. S. Severin
- Book ID
- 111538037
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 449 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0006-2979
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract Angiogenesis is the process by which new blood vessels are formed from preexisting vasculature. It is an essential feature of the female reproductive cycle, embryonic development and wound repair. Angiogenesis has also been identified as a causal or contributing factor in several pathol
We report here that tumor angiogenesis-mediated endothelial cell (EC) anergy can be overcome by inhibitors of angiogenesis. We found previously that tumor growth, known to be dependent on angiogenesis, results in down-regulation of endothelial adhesion molecules and tumor EC anergy to inflammatory s
## Abstract FK228 (formerly FR901228) was recently isolated from __Chromobacterium violaceum__ as a potent antitumor agent and its biologic target protein was identified as histone deacetylase (HDAC). Because of its unique chemical structure (__i.e.__, bicyclic depsipeptide) and activity profile in