## Background and objectives: Although the relationship between angiogenesis and tumor proliferation or malignant potential has been previously demonstrated in several studies, early stage of cancer invasion and angiogenesis has seldom been investigated. ## Methods: From the esophageal specimens
Tumor Angiogenesis in Vulvar Squamous Cell Carcinoma
โ Scribed by Faisal Qureshi; Adnan Munkarah; Mousumi Banerjee; Suzanne M. Jacques
- Book ID
- 112247556
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 1020 KB
- Volume
- 72
- Category
- Article
- ISSN
- 0090-8258
No coin nor oath required. For personal study only.
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Background. Angiogenesis is necessary for tumor growth and metastasis. In breast and other cancers angiogenesis has been shown to correlate with tumor size, metastatic potential, and prognosis. Some studies of head and neck cancer have shown a similar correlation, although results are inconclusive.
Squamous cell carcinoma (SCC) antigen levels were studied in 34 patients with primary (N = 27) or recurrent (N = 7) SCC of the vulva. In primary disease, the SCC antigen level was greater than 2.5 ng/ml in only four patients ( 15 %) . Elevated antigen levels ranged from 2.7-1 8 .O ng/ml . All of the