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Tues-P33 - In vitro metabolism of S-(+)- and R-(-)-enantiomers of mirtazapine

โœ Scribed by L.P.C. Delbressine; R.M.E. Vos; R. Pinder


Book ID
119574113
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
131 KB
Volume
13
Category
Article
ISSN
0924-9338

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In vitro metabolism of mirtazapine enant
โœ Seetal Dodd; David W. Boulton; Graham D. Burrows; C. Lindsay De Vane; Trevor R. ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 52 KB ๐Ÿ‘ 1 views

The metabolism of mirtazapine enantiomers was investigated in vitro using human lymphoblast microsomes transfected with human cDNA to overexpress either CYP1A2, CYP2C9, CYP2C19, CYP2D6 or CYP3A4 and assayed for mirtazapine enantiomers using a validated chiral method of high-performance liquid chroma