Significant antitumor activity of oncoly
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Ling Feng He; Jin Fa Gu; Wen Hao Tang; Jun Kai Fan; Na Wei; Wei Guo Zou; Yan Hon
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Article
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2008
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John Wiley and Sons
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English
β 497 KB
## Abstract ## Background Human interferonβΞ² (IFNβΞ²) has been widely used in gene therapy for its antitumor activity but its therapeutic effect is limited. The conditionally replicative adenovirus ONYXβ015 (a E1Bβ55βkDaβdeleted adenovirus) targets well to tumor cells, but is not potent enough to c