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TSC1/TSC2 signaling in the CNS

✍ Scribed by Juliette M. Han; Mustafa Sahin


Book ID
113622423
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
473 KB
Volume
585
Category
Article
ISSN
0014-5793

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Tuberous sclerosis complex (TSC) is a severe autosomal-dominant disorder characterized by the development of benign tumors (hamartomas) in many organs. It can lead to intellectual handicap, epilepsy, autism, and renal or heart failure. An inactivating mutation in either of two tumor-suppressor genes