Analysis of 65 tuberous sclerosis comple
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Nanna D. Rendtorff; Bolette Bjerregaard; Morten Frödin; Susanne Kjaergaard; Hann
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Article
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2005
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John Wiley and Sons
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English
⚖ 292 KB
Tuberous sclerosis complex (TSC) is a severe autosomal-dominant disorder characterized by the development of benign tumors (hamartomas) in many organs. It can lead to intellectual handicap, epilepsy, autism, and renal or heart failure. An inactivating mutation in either of two tumor-suppressor genes