Tryptophan hydroxylase polymorphism and suicidality in unipolar and bipolar affective disorders: a multicenter association study
✍ Scribed by Daniel Souery; Sophie Van Gestel; Isabelle Massat; Sylvie Blairy; Rolf Adolfsson; Douglas Blackwood; Jurgen Del-Favero; Dimitris Dikeos; Miro Jakovljevic; Radka Kaneva; Enrico Lattuada; Bernard Lerer; Roberta Lilli; Vihbra Milanova; Walter Muir; Markus Nöthen; Lilijana Oruc; George Papadimitriou; Peter Propping; Thomas Schulze; Alessandro Serretti; Baruch Shapira; Enrico Smeraldi; Costas Stefanis; Marian Thomson; Christine Van Broeckhoven; Julien Mendlewicz
- Book ID
- 119408405
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 36 KB
- Volume
- 49
- Category
- Article
- ISSN
- 0006-3223
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📜 SIMILAR VOLUMES
Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in the synthesis of 5-hydroxytryptamine (5-HT). An association study in bipolar affective disorder I or unipolar major affective disorder was performed by using a Bfa I restriction site polymorphism within intron 7 of the tryptophan hydroxylas
## Abstract Convincing evidence for a genetic component in the etiology of affective disorders (AD), including bipolar affective disorder (BPAD) and unipolar affective disorder (UPAD), is supported by traditional and molecular genetic studies. Most arguments lead to the complex inheritance hypothes