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True tracer radiolabeling of gadolinium complex of 10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7 triacetic acid (HP-DO3A)

✍ Scribed by Krishan Kumar; K. Sukumaran; C. Allen Chang; M. F. Tweedle; W. C. Eckelman

Publisher
John Wiley and Sons
Year
1993
Tongue
French
Weight
446 KB
Volume
33
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

True tracer radiolabeling, purification, and analysis of a gadolinium complex of HP‐DO3A (10‐(2‐hydroxy‐propyl)‐1,4,7,10‐tetraazacyclo dodecane‐1,4,7‐triacetic acid) was achieved by the reaction of carrier‐added ^153^GdCl~3~ and excess free ligand. Two analytical methods (ITLC and HPLC) were developed to determine the purity of radiolabeled samples.

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