✦ LIBER ✦

Trtamcinolone-induced systemic infections in female mice

✍ Scribed by Israela Berdicevsky; Michael Silbermann

Publisher: John Wiley and Sons
Year: 1976
Tongue: English
Weight: 680 KB
Volume: 119
Category: Article
ISSN: 0022-3417
DOI: 10.1002/path.1711190109

No coin nor oath required. For personal study only.

✦ Synopsis

Six-week-old female mice were injected for prolonged periods of time with a synthetic glucocorticoid (triamcinolone diacetate). With the progression of the experiment the mortality rate increased significantly. Tissue samples were obtained from the surviving animals after 10, 22, 35 and 45 consecutive daily injections. Cultures were obtained from kidney and liver homogenates as well as from blood samples. Quantitative measurements indicated severe renal and hepatic infections which were followed by bactoeremia. The prevalent organisms in all cultures were enterobacteriae such as E. coli, Klebsiella, Pseudomonas and Streptococcus fecalis. Placebo-control animals which received daily injections of the vehicle revealed a moderate, transient infection.

📜 SIMILAR VOLUMES

Induced dominant lethals in female mice

✍ R. Hess 📂 Article 📅 1973 🏛 SP Birkhäuser Verlag Basel 🌐 English ⚖ 93 KB

Lead-induced leukocytosis in female mice

✍ G. R. Hogan; D. P. Adams 📂 Article 📅 1979 🏛 Springer-Verlag 🌐 English ⚖ 287 KB

Lead acetate was shown to stimulate a striking leukocytosis in young adult female mice. The effect was manifest 4 days after lead injection and continued throughout the following 4 days. At the higher treatment level, lead induced an increase of 300% for both monocytes and neutrophils. The leukocyto

Characterization of diethylstilbestrol-i

Characterization of diethylstilbestrol-induced hypospadias in female mice

✍ Miyagawa, Shinichi ;Buchanan, David L. ;Sato, Tomomi ;Ohta, Yasuhiko ;Nishina, Y 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 477 KB 👁 1 views

DSCG Reduces RSV-induced illness in RSV-

DSCG Reduces RSV-induced illness in RSV-infected mice

✍ Koichi Hashimoto; Syuichi Mori; Yuko Hashimoto; Hisatoshi Kaneko; Kei Ishibashi; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB

## Abstract Respiratory syncytial virus (RSV) is one of the pathogens generally associated with the common cold, lower respiratory infection, and exacerbation of asthma. Disodium cromoglycate (DSCG) is a safe and widely used drug for the prevention of bronchial asthma and allergic rhinitis attacks.

Antigen-induced protection against infec

Antigen-induced protection against infection withToxocara vitulorumlarvae in mice

✍ P. H. Amerasinghe; R. P. V. J. Rajapakse; S. Lloyd; S. T. Fernando 📂 Article 📅 1992 🏛 Springer-Verlag 🌐 English ⚖ 523 KB

Female sex hormones suppress development

Female sex hormones suppress development of collagen-induced arthritis in mice

✍ Rikard Holmdahl; Liselott Jansson; Mikael Andersson 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 717 KB

We have previously reported that male DBM1 mice are more susceptible to collagen-induced arthritis than are females. Here we report that oophorectomy makes female mice as susceptible to collagen arthritis as are normal males. Induction of collagen-induced arthritis in mice is a T cellaependent proce