✦ LIBER ✦

Trophoblast regeneration by inner cell masses isolated from cultured mouse embryos

✍ Scribed by Spindle, Akiko I.

Publisher: John Wiley and Sons
Year: 1978
Tongue: English
Weight: 393 KB
Volume: 203
Category: Article
ISSN: 0022-104X
DOI: 10.1002/jez.1402030315

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The developmental potential of the inner cell mass (ICM) of the cultured mouse embryo was determined by testing the ability of the ICM to regenerate trophoblast in vitro. ICM's isolated by immunosurgery from either single or chimeric embryos were able to regenerate trophoblast when they were isolated at 69 hours of culture from the 2‐cell stage, but they had lost this capacity by 93 hours of culture. Trophoblast regeneration by isolated ICM's did not appear to require either a critical cell mass at the time of isolation or cell proliferation during regeneration.

📜 SIMILAR VOLUMES

Apparent trophoblast giant cell producti

Apparent trophoblast giant cell production in vitro by core cells isolated from cultured mouse inner cell masses

✍ Wiley, Lynn M. 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB

## Abstract Mouse ICM's that were isolated from blastocysts by immunosurgery and subsequently cultured for four to five days were tested for their ability to form trophoblast giant cells (TGC's) in vitro. The cores were isolated from such ICM's by a second immunosurgery and cultured for 7 to 14 day