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Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines

✍ Scribed by Myung-Ae Bae; Herman Rhee; Byoung J Song

Book ID
119537539
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
323 KB
Volume
139
Category
Article
ISSN
0378-4274

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## Abstract ## BACKGROUND Ligand activation of peroxisome proliferator‐activated receptor Ξ³ (PPARΞ³) results in the inhibition of proliferation of various cancer cells. The aim of this study is to investigate the mechanisms of cell growth inhibition of hepatocellular carcinoma (HCC) cell lines by t