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Tangeretin and nobiletin induce G1 cell cycle arrest but not apoptosis in human breast and colon cancer cells

✍ Scribed by Karen L. Morley; Peter J. Ferguson; James Koropatnick

Book ID: 116334340
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 382 KB
Volume: 251
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2006.11.016

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## Abstract Breast cancer (BC) is the leading cancer in the world in terms of incidence and mortality in women. However, the mechanism by which BC develops remains largely unknown. The increase in cytosolic free Ca^2+^ can result in different physiological changes including cell growth and death. O