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Tritium labelling of pharmaceuticals by metal-catalysed exchange methods

✍ Scribed by D. Hesk; C. F. Lavey; P. McNamara

Publisher
John Wiley and Sons
Year
2010
Tongue
French
Weight
201 KB
Volume
53
Category
Article
ISSN
0022-2135

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✦ Synopsis

Abstract

Metal‐catalysed exchange with tritiated water and tritium gas has been extensively used to prepare a wide range of tritium‐labelled compounds in support of pharmaceutical research. Examples of the utility of both heterogeneous and homogeneous metal catalysts to label a very broad range of structures will be discussed in this review. Copyright Β© 2010 John Wiley & Sons, Ltd.

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