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Tritium labeling of 3,2′-dimethyl-4-aminobiphenyl by catalytic exchange

✍ Scribed by Matthew W. Noall

Publisher
John Wiley and Sons
Year
1969
Tongue
French
Weight
184 KB
Volume
5
Category
Article
ISSN
0022-2135

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Benzimidazole carbamates (BZCs) act as inhibitors of the tubulin-microtubule equilibria in eukaryotic organisms. Recently drug resistance to this class of compounds in helminth parasites has been shown to be due to a reduced ability of resistant tubulin to bind BZCs. In order to quantitate the natur