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Tritiated 2-deoxy-d-glucose as a probe for cell membrane permeability studies

✍ Scribed by Erik Walum; Anders Peterson

Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
309 KB
Volume
120
Category
Article
ISSN
0003-2697

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✦ Synopsis

Tritiated 2-deoxy-D-glucose was taken up and phosphorylated by cultured cells of neuronal (NIE 115) glial (138 MG), muscle (L 6) and liver (BRL 123) origin. Upon perfusion the cells slowly released 2-deoxy-D-glucose 6-phosphate. The following values for rate constants, half-lives, and activation energies for the efflux were obtained:

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