TRISOMY FOR CHROMOSOME 22
โ Scribed by TURNER, B
- Book ID
- 123228639
- Publisher
- The Lancet
- Year
- 1961
- Tongue
- English
- Weight
- 349 KB
- Volume
- 278
- Category
- Article
- ISSN
- 0140-6736
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We report on a case of generalized mosaicism for trisomy 22. At chorionic villus sampling (CVS) in the 37th week of pregnancy, a 47,XX,+22 karyotype was detected in all cells. The indication for CVS was severe unexplained symmetrical intrauterine growth retardation (IUGR) and a ventricular septal de
## Abstract Trisomy 22 is one of the most common trisomies in clinically recognized pregnancies, yet relatively little is known about the origin of nondisjunction for chromosome 22. Accordingly, we initiated studies to investigate the origin of the extra chromosome in 130 trisomy 22 cases. Our resu