Trisomy 4q syndrome: presentation of a new case and review of the literature
✍ Scribed by Catarina Lundin; Lore Zech; Kerstin Sjörs; Claes Wadelius; Göran Annerén
- Book ID
- 113987291
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 128 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0003-3995
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I have read with great interest the paper by Crowe et al. [1997]. It is an excellent clinical and cytogenetic review of trisomy 22 in its various manifestations. I only wish to point out that the first proven case (by G-banding) of trisomy 22 appeared in 1973, in a paper in which we demonstrated the
In a case of mosaic trisomy 22 the trisomic cells were detected primarily in fibroblasts. Results of initial lymphocyte chromosome analysis were normal. However, mosaicism was suspected because the patient had hypomelanosis of Ito, hemiatrophy, failure to thrive, and mental retardation. Mosaicism wa