TRISOMY 20 MOSAICISM IN AMNIOTIC FLUID CELLS
โ Scribed by Mascarello, J.T.; Chadwick, D.L.; Moyers, T.G.
- Book ID
- 123137010
- Publisher
- The Lancet
- Year
- 1980
- Tongue
- English
- Weight
- 147 KB
- Volume
- 315
- Category
- Article
- ISSN
- 0140-6736
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Trisomy 16 mosaicism was found in amniotic fluid cells in a patient undergoing amniocentesis because of elevated second-trimester maternal serum alpha-fetoprotein (MSAFP) (2.80 MOM), a markedly elevated human chorionic gonadotropin level (hCG) (12.02 MOM), and a Down syndrome risk of 1:55. Ultrasoun
Nine new cases of prenatally detected true mosaic trisomy 20 (T20) are reported. In three instances the fetuses were aborted. One fetus showed multiple malformations associated with a high percentage of T20 cells among amniotic fluid (AF) cells and fibroblasts of different fetal tissues. In two othe