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Trisomy 20 mosaicism in amniotic fluid cell culture

โœ Scribed by N. C. Nevin; J. Nevin; W. Thompson


Book ID
119838925
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
241 KB
Volume
15
Category
Article
ISSN
0009-9163

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Trisomy 16 mosaicism was found in amniotic fluid cells in a patient undergoing amniocentesis because of elevated second-trimester maternal serum alpha-fetoprotein (MSAFP) (2.80 MOM), a markedly elevated human chorionic gonadotropin level (hCG) (12.02 MOM), and a Down syndrome risk of 1:55. Ultrasoun

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Nine new cases of prenatally detected true mosaic trisomy 20 (T20) are reported. In three instances the fetuses were aborted. One fetus showed multiple malformations associated with a high percentage of T20 cells among amniotic fluid (AF) cells and fibroblasts of different fetal tissues. In two othe