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Trisomy 15, Sex Chromosome Loss, and Hematological Malignancy

✍ Scribed by Brian J Baumgartner; Muhammad Shurafa; Howard Terebelo; Efstathios Tapazoglou; Daniel L Van Dyke


Book ID
114137015
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
95 KB
Volume
117
Category
Article
ISSN
0165-4608

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Clonal origin and trisomy of chromosome
✍ Philip J. Fialkow; A. Lakshma Reddy; Jean I. Bryant πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 French βš– 537 KB

## Abstract During the course of a multifaceted study of clonality in murine neoplasms we observed two B‐lymphoid malignancies. Results of studies with the X‐chromosome‐linked enzyme phosphoglycerate kinase strongly suggest that these tumors had a clonal origin. Each of them had trisomy 15. This ch