Triple-quantum-coherence-filtered imaging of sodium ions in vivo at 4.7 tesla

✍ Scribed by Richard H. Griffey; Beatrice V. Griffey; Nicholas A. Matwiyoff

• Publisher: John Wiley and Sons
• Year: 1990
• Tongue: English
• Weight: 431 KB
• Volume: 13
• Category: Article
• ISSN: 0740-3194
• DOI: 10.1002/mrm.1910130213

✦ Synopsis

Abstract

The tissue distribution of sodium ions which generate triple‐quantum coherence (TQC) in vivo is determined from images. A technique for filtering conventional sodium images, so that signal is obtained only from sodium ions which have a correlation time appropriate for producing TQC, is described. The utility of TQC‐filtered sodium images is demonstrated in a study of tumors implanted in a nude rat model, where the intensity of the TQC signal from sodium ions in the growing margin of the tumor is observed to be 200‐250% greater than that from surrounding tissue.