## Abstract The tissue distribution of sodium ions which generate tripleβquantum coherence (TQC) __in vivo__ is determined from images. A technique for filtering conventional sodium images, so that signal is obtained only from sodium ions which have a correlation time appropriate for producing TQC,
In Vivo Triple Quantum Filtered Twisted Projection Sodium MRI of Human Articular Cartilage
β Scribed by Arijitt Borthakur; Ileana Hancu; Fernando E. Boada; Gary X. Shen; Erik M. Shapiro; Ravinder Reddy
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 150 KB
- Volume
- 141
- Category
- Article
- ISSN
- 1090-7807
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β¦ Synopsis
In this work, we present the first triple quantum filtered (TQF) sodium MR images of the human knee joint in vivo. A 3D TQF data set of 16 slices was obtained in 20 min using a TQF pulse sequence preencoded to a twisted projection imaging readout. Images clearly demarcate patellar cartilage and also demonstrate fluid signal suppressed by the triple quantum filter. Biexponential transverse relaxation times were calculated by fitting the TQF free induction decay to a theoretical signal expression. The average values from three healthy volunteers were T * 2fall β«Ψβ¬ 9.59 Ψ 0.35 ms and T * 2rise β«Ψβ¬ 0.84 Ψ 0.06 ms. Application of TQF imaging in biological tissues is discussed.
π SIMILAR VOLUMES
We have derived the differential equations that describe the dynamics of spin-3/2 nuclei in the presence of radiofrequency (RF) fields and both static and fluctuating quadrupolar interactions. The formalism presented was used to predict the sodium triplequantum-filtered (TQ-filtered) signal loss in