Owing to differences in maternal serum alpha-fetoprotein, human chorionic gonadotrophin and oestriol levels between native Japanese and Caucasian women screened in this labortory, a study was conducted to measure amniotic fluid alpha-fetoprotein (AFAFP) levels in native Japanese pregnancies. When th
TRIPLE MARKER SCREENING IN NATIVE JAPANESE WOMEN
β Scribed by TAKEKAZU ONDA; MICHIHIRO KITAGAWA; OSAMU TAKEDA; HARUHIKO SAGO; KEN KUBONOYA; KAZUSO IINUMA; LINDA A. BRADLEY; JACOB A. CANICK; NATALIE E. KRASIKOV; NAN R. PONTING; ROBERT E. GRIER
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 390 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0197-3851
No coin nor oath required. For personal study only.
β¦ Synopsis
Prenatal screening using the maternal serum markers alpha-fetoprotein, human chorionic gonadotropin, and unconjugated oestriol was investigated in a native Japanese population. Comparison with a Caucasian U.S. population revealed differences which led to modification of the generally used equations for risk calculations. Prenatal screening was shown to be clinically useful.
π SIMILAR VOLUMES
Based on 9350 pregnant Japanese women who were screened by serum triple-marker determination, accuracy of predicted risk for Down syndrome was examined using 24 Down syndrome cases detected either prenatally or postnatally. The correlation is statistically very high (r=0β’98) between the predicted ri
## Abstract Congenital heart defects (CHDs) are the most common of all birth defects. For many newborns with a CHD, prenatal versus postnatal detection is associated with substantially decreased morbidity and mortality risks. Although technological advances in fetal echocardiography have led to an
## Abstract Excretion of 1,__N__^__6__^βethenodeoxyadenosine (Ο΅dA), a marker for lipid peroxidation (LPO)βderived DNA damage was analyzed in urine of nonsmoking postmenopausal women participating in a dietary intervention trial in Northern Japan. Hereby the efficacy of dietary consultation in reduc