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Triple-Helix Formation of Oligodeoxynucleotides Containing [(3′S,5′R)-2′-Deoxy-3′,5′-ethano-β-D-ribofuranosyl]nucleosides (“Bicyclo-deoxynucleosides”)

✍ Scribed by Martin Bolli; Prof. Dr. Christian Leumann

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
416 KB
Volume
34
Category
Article
ISSN
0044-8249

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✦ Synopsis

Under the conditions of single-salt gradients (0.5 M KCl/O.l M KCI), the channel formed by 1 a showed a reversal potential of 35.9 mV, indicating that it has a distinct selectivity for cations over anions. The permeability ratio PK+/Pc,of 20, calculated

📜 SIMILAR VOLUMES

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Nucleic-Acid Analogues with Constraint Conformational Flexibility in the Sugar-Phosphate Backbone 'Tricyclo-DNA'. Part 1. Preparation of [(5'R,6'R)-2'-Deoxy-3',5'-ethano-5',6'-methano-β-D-ribofuranosyl] thymine and -adenine, and the Corresponding Phosphoramidites for Oligonucleotide Synthesis. -An