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Triphenylphosphine/germanium(IV) chloride combination: A new agent for the reduction of α-bromo carboxylic acid derivatives

✍ Scribed by Hirotaka Kagoshima; Yukihiko Hashimoto; Dai Oguro; Takaaki Kutsuna; Kazuhiko Saigo


Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
196 KB
Volume
39
Category
Article
ISSN
0040-4039

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Triphenylphosphine/scandium(III) trifluo
✍ Hirotaka Kagoshima; Yukihiko Hashimoto; Kazuhiko Saigo 📂 Article 📅 1998 🏛 Elsevier Science 🌐 French ⚖ 136 KB

The Ph3P/Sc(OTf)3 combination was found to be effective for the Reformatsky reaction; when ~-bromo carboxylic acid derivatives were allowed to react with aldehydes in the presence of the Ph3P/Sc(OTf) 3 combination, the corresponding [3-hydroxy carboxylic acid derivatives were obtained in good yields