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Triorganozincates as efficient nucleophiles for the diastereoselective addition to N-(tert-butanesulfinyl)imines

โœ Scribed by Raquel Almansa; David Guijarro; Miguel Yus


Book ID
108284313
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
111 KB
Volume
19
Category
Article
ISSN
0957-4166

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Application of the addition of triorgano
โœ Raquel Almansa; David Guijarro; Miguel Yus ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 265 KB

Highly enantiomerically enriched N-protected a-amino acids can be easily prepared from optically pure N-(tert-butanesulfinyl)imines by a four-step sequence involving: diastereoselective addition of a triorganozincate to the imine, removal of the sulfinyl group, benzoylation of the nitrogen atom of t