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Trimethylsilyl-Directed 1,3-Dipolar Cycloaddition Reactions in the Solid-Phase Synthesis of 1,2,3-Triazoles

โœ Scribed by Coats, Steven J.; Link, Jeffrey S.; Gauthier, Diane; Hlasta, Dennis J.


Book ID
119993871
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
201 KB
Volume
7
Category
Article
ISSN
1523-7060

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Regiospecific synthesis of 2-allyl-1,2,3
โœ Shin Kamijo; Tienan Jin; Zhibao Huo; Yoshinori Yamamoto ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 129 KB

2-Allyl-1,2,3-triazoles were prepared by the palladium-catalyzed three component coupling (TCC) reaction of alkynes, allyl methyl carbonate and trimethylsilyl azide. A p-allylpalladium azide complex, which undergoes the 1,3-dipolar cycloaddition with alkynes, is proposed as a key intermediate in the