TRIM Proteins: Another Class of Viral Victims
β Scribed by Munir, M.
- Book ID
- 121466715
- Publisher
- American Association for the Advancement of Science (AAAS)
- Year
- 2010
- Tongue
- English
- Weight
- 805 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1945-0877
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## TAP1-independent loading of class I molecules by exogenous viral proteins Presentation of peptides derived from endogenous proteins on class I molecules needs functional TAP peptide transporters. To reveal whether class I-associated presentation of exogenous proteins also required the presence
## Abstract The TRIM/RBCC proteins are defined by the presence of the tripartite motif composed of a RING domain, one or two Bβbox motifs and a coiledβcoil region. These proteins are involved in a plethora of cellular processes such as apoptosis, cell cycle regulation and viral response. Consistent