Trilineage response to recombinant human granulocyte colony-stimulating factor administration in a patient with myelodysplastic syndrome
✍ Scribed by Caroline Rey; Brigiette Bader-Meunier; Gérard Tertian; Francçise Mielot; Gil Tchernia; Antoine Yver
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 368 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0361-8609
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A therapeutic trial of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) was attempted in a patient with neutropenia and frequent infections secondary to T-y lymphoproliferative disease (T-y LPD). During the 14 days of subcutaneous rhGM-CSF (500 kg/m2/day), the absolute e
The hematopoietic system in patients with aplastic anemia (AA) shows both quantitative and qualitative deficiencies, i.e., reduced numbers of hematopoietic progenitor cells (HPC) and impaired HPC proliferation in long-term marrow cultures (LTMC). Since recombinant human granulocyte macrophage-colony