✦ LIBER ✦

Triggering TLR signaling in vaccination

✍ Scribed by David van Duin; Ruslan Medzhitov; Albert C. Shaw

Book ID: 116577727
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 242 KB
Volume: 27
Category: Article
ISSN: 1471-4906
DOI: 10.1016/j.it.2005.11.005

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## Abstract The family of Toll‐like receptors (TLRs) expressed by innate immune cells recognizes a spectrum of microbial components as well as molecules released from injured tissues. TLR ligation activates intracellular signaling cascades that culminate in the up‐regulation of proinflammatory gene